Immobilization stress effect on thyroid hormone secretion

Thyroid Hormone Synthesis and Secretion

Chapter 2 Thyroid Hormone Synthesis and Secretion

The main function of the thyroid gland is to make hormones, T4 and T3, which are essential for the regulation of metabolic processes throughout the body. As at any factory, effective production depends on three key components adequate raw material, efficient machinery, and appropriate controls. Iodine is the critical raw material, because 65% of T4 weight is iodine. Ingested iodine is absorbed ...

Effect of growth hormone on insulin secretion.

MALAISE, WILLY J., FRANCXNE MALAISSE-LAGAE, SUZANNE KING, ANII PETER H. WRIGHT. Efect of growth hormone on insulin secretion. Am. J. Physiol. 215(2) : 4-23-428. 1968.pInsulin secretion by pancreatic tissue or isolated islets of the normal rat is not affected by addition of ovine or rat growth hormone to the incubation medium. Pancreatic tissue removed from hypophysectomized rats secretes an abn...

Thyroid Hormone Response Element Half-Site Organization and Its Effect on Thyroid Hormone Mediated Transcription

Thyroid hormone (TH) exerts its effects by binding to the thyroid hormone receptor (TR), which binds to TH response elements (TREs) to regulate target gene expression. We investigated the relative ability of liganded homodimers TR and retinoid X receptor (RXR), and the heterodimer TR/RXR, to regulate gene expression for the TRE half-site organizations: direct repeat 4 (DR4), inverted repeat 0 (...

Oxidative stress impact on growth hormone secretion in the eye

AIM To evaluate the influence of oxidative stress on extrapituitary growth hormone (GH) secretion in the eye and to analyze the interdependence between eye and serum GH levels under normal and hypoxic conditions. METHODS Pars plana vitrectomy (PPV) was performed in 32 patients with developed proliferative diabetic retinopathy (PDR) and 49 non-diabetic controls, both of whom required this proc...